Extensive Leptomeningeal
Extensive Leptomeningeal
This case of neurosarcoidosis of the spinal cord involved several meningeal areas and spinal cord levels. It appears to be the tenth autopsy-documented case of neurosarcoidosis of the spinal cord, though the patient had more extensive spinal cord disease than has been previously reported.
Sarcoidosis is a granulomatous disease, usually involving the lungs, eye, striated muscle, and soft tissues. In a few cases, the central nervous system (CNS) is involved, which may be either primary or secondary. Neurosarcoidosis with typical non-necrotizing granulomas located in the leptomeninges and within the parenchyma of the spinal cord is a rare finding. Because a large number of conditions may clinically mimic neurosarcoidosis, histopathologic confirmation is of paramount importance in establishing the definitive diagnosis.
This case of neurosarcoidosis of the spinal cord involved several meningeal areas and spinal cord levels. It appears to be the tenth autopsy-documented case of neurosarcoidosis of the spinal cord, though the patient had more extensive spinal cord disease than has been previously reported.
Sarcoidosis is a granulomatous disease, usually involving the lungs, eye, striated muscle, and soft tissues. In a few cases, the central nervous system (CNS) is involved, which may be either primary or secondary. Neurosarcoidosis with typical non-necrotizing granulomas located in the leptomeninges and within the parenchyma of the spinal cord is a rare finding. Because a large number of conditions may clinically mimic neurosarcoidosis, histopathologic confirmation is of paramount importance in establishing the definitive diagnosis.
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