Extensive Leptomeningeal

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Extensive Leptomeningeal
This case of neurosarcoidosis of the spinal cord involved several meningeal areas and spinal cord levels. It appears to be the tenth autopsy-documented case of neurosarcoidosis of the spinal cord, though the patient had more extensive spinal cord disease than has been previously reported.

Sarcoidosis is a granulomatous disease, usually involving the lungs, eye, striated muscle, and soft tissues. In a few cases, the central nervous system (CNS) is involved, which may be either primary or secondary. Neurosarcoidosis with typical non-necrotizing granulomas located in the leptomeninges and within the parenchyma of the spinal cord is a rare finding. Because a large number of conditions may clinically mimic neurosarcoidosis, histopathologic confirmation is of paramount importance in establishing the definitive diagnosis.

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