Clopidogrel and Proton-Pump Inhibitors: News on the Noise
Clopidogrel and Proton-Pump Inhibitors: News on the Noise
Citation: Ray WA, Murrray KT, Griffin MR, et al. Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study. Ann Intern Med. 2010;152:337-345.
O'Donoghue ML, Braunwald E, Antman EM, et al. Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials. Lancet. 2009;374:989-997.
FDA. Plavix (clopidogrel): Reduced effectiveness in patients who are poor metabolizers of the drug. March 12, 2010. Available at: http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm204256.htm Accessed March 26, 2010
Johnson DA. Proton-pump inhibitors and clopidogrel – friends or foes? Medscape Gastroenterology. September 30, 2009. Available at: http://www.medscape.com/viewarticle/709685 Accessed March 26, 2010
Citation: Ray WA, Murrray KT, Griffin MR, et al. Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study. Ann Intern Med. 2010;152:337-345.
O'Donoghue ML, Braunwald E, Antman EM, et al. Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials. Lancet. 2009;374:989-997.
FDA. Plavix (clopidogrel): Reduced effectiveness in patients who are poor metabolizers of the drug. March 12, 2010. Available at: http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm204256.htm Accessed March 26, 2010
Johnson DA. Proton-pump inhibitors and clopidogrel – friends or foes? Medscape Gastroenterology. September 30, 2009. Available at: http://www.medscape.com/viewarticle/709685 Accessed March 26, 2010
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