Reduction of Advance Glycation End Products (AGEs)
The browning of proteins by sugars is not the only element that leads to aging.
But it is one that we can do something about.
Preventing diabetes is the most straightforward way.
A number of widely available supplements have also been shown to reduce the accumulation of AGEs.
Most antioxidants have significant AGE-inhibitory activity.
However, some have important additional effects.
A number of widely available supplements have been shown to reduce the accumulation of AGEs.
These are worth considering as additions to your diet: 1.
Thiamine (Vitamin B1) can reduce the AGE generation inside the body.
Diets high in fiber often contain useful amounts of thiamine.
Our thiamine reserves can be depleted by chronic alcohol consumption, which is best avoided on many fronts.
The best way to get thiamine is to take special forms that have improved absorption properties.
These are naturally found in garlic and onions.
Botanically, these plants are of the alum family.
These chemicals are called allithiamines, the best studied of which is benfotiamine.
2.
Pyridoxamine (a derivative of Vitamin B6) is able to reduce the formation of AGEs, particularly those derived from fats.
Pyridoxamine is safe and well tolerated as a supplement, and has been shown to be effective in reducing AGE levels and in preventing some of the complications of aging and diabetes in animals.
3.
Rytine, a natural flavonoid found in high concentration in tomato juice, has the ability to inhibit AGE formation.
4.
Carnosine (an antioxidant from meat, typically lacking in a vegetarian diets) inhibits AGE formation and prevents protein modification by acting as a scavenger.
5.
Alpha-lipoic acid (highest in foods such as potatoes, carrots, broccoli, beets and yams) can prevent AGE-modification.
But it is one that we can do something about.
Preventing diabetes is the most straightforward way.
A number of widely available supplements have also been shown to reduce the accumulation of AGEs.
Most antioxidants have significant AGE-inhibitory activity.
However, some have important additional effects.
A number of widely available supplements have been shown to reduce the accumulation of AGEs.
These are worth considering as additions to your diet: 1.
Thiamine (Vitamin B1) can reduce the AGE generation inside the body.
Diets high in fiber often contain useful amounts of thiamine.
Our thiamine reserves can be depleted by chronic alcohol consumption, which is best avoided on many fronts.
The best way to get thiamine is to take special forms that have improved absorption properties.
These are naturally found in garlic and onions.
Botanically, these plants are of the alum family.
These chemicals are called allithiamines, the best studied of which is benfotiamine.
2.
Pyridoxamine (a derivative of Vitamin B6) is able to reduce the formation of AGEs, particularly those derived from fats.
Pyridoxamine is safe and well tolerated as a supplement, and has been shown to be effective in reducing AGE levels and in preventing some of the complications of aging and diabetes in animals.
3.
Rytine, a natural flavonoid found in high concentration in tomato juice, has the ability to inhibit AGE formation.
4.
Carnosine (an antioxidant from meat, typically lacking in a vegetarian diets) inhibits AGE formation and prevents protein modification by acting as a scavenger.
5.
Alpha-lipoic acid (highest in foods such as potatoes, carrots, broccoli, beets and yams) can prevent AGE-modification.
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